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Brian E. Persing, M.D.

Brian E. Persing, M.D.

Director of the Mitchell Cancer InstituteAssociate Professor of Interdisciplinary Clinical Oncology; Medical Oncologist and HematologistSpecialty: Cancer Care
Or call to make an appointment+1(251) 410-1010

About Brian Persing, M.D.

Brian Persing, M.D., is director of the USA Health Mitchell Cancer Institute (MCI) and an associate professor of interdisciplinary clinical oncology at USA Health. A nationally recognized medical oncologist and hematologist, Persing provides patient-centered cancer care while leading the institute’s clinical, research and strategic initiatives.

Persing previously served at MCI from 2020 to 2024 and returned in 2026 to lead the region’s premier academic cancer center. He is triple board-certified in internal medicine, hematology and medical oncology, with a clinical focus on lung cancer. He earned his medical degree from the University of South Dakota School of Medicine and completed his internship, residency and fellowship in hematology and oncology at the University of Mississippi Medical Center.

At the national level, Persing is a respected leader in oncology and health policy. In 2025, he was inducted as a Fellow of the American Society of Clinical Oncology (FASCO). He has held numerous leadership roles within ASCO, including chair of the State Affiliate Council, association board member and treasurer, and advocacy representative. In this capacity, he has provided expert testimony before the U.S. House of Representatives Appropriations Subcommittee on Education and Health and Human Services, helping advance policies that expand access to high-quality cancer care and clinical trials.

In addition to his national leadership, Persing has played a key role in advancing oncology care and education across the Gulf Coast and Mississippi. He previously served as division chair of hematology and oncology at MCI and interim program director for the medical oncology fellowship program at the University of South Alabama Frederick P. Whiddon College of Medicine. He has also held academic appointments at William Carey University College of Osteopathic Medicine and the Whiddon College of Medicine.

Persing is an active member of several professional organizations, including the American College of Physicians, American Society of Hematology, International Association for the Study of Lung Cancer, American Medical Association and Mississippi State Medical Association. His research and publications focus on improving cancer care delivery, outcomes and patient access to innovative therapies.

Committed to improving outcomes for patients across the Gulf Coast, Persing remains actively involved in patient care, ensuring a strong connection between clinical practice and the institute’s mission to deliver compassionate, cutting-edge cancer treatment close to home. 

Conditions Treated

  • Breast Cancer
  • GI malignancies
  • Lung Cancer

Board Certifications

  • American Board of Internal Medicine
  • American Board of Internal Medicine: Hematology
  • American Board of Internal Medicine: Oncology

Education

  • Medical School: University of South Dakota School of Medicine | Vermillion, SD
  • Residency (Internal Medicine): University of Mississippi Medical Center | Jackson, MS
  • Fellowship (Hematology and Oncology): University of Mississippi Medical Center | Jackson, MS

Professional Memberships

  • American College of Physicians 
  • American Society of Clinical Oncology 
  • American Society of Hematology 
  • Mississippi Oncology Society
  • International Association for the Study of Lung Cancer
  • American Medical Association
  • Mississippi State Medical Association

Languages

  • English
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