Singh A

Ajay P. Singh, Ph.D.

Program Leader of Cancer Biology and Cancer Health DisparitiesProfessor of Oncologic Sciences; Professor of Biochemistry and Molecular Biology; Head, Tumor Microenvironment LaboratorySpecialty: Cancer CareEmail Researcher

About Ajay Singh

Dr. Ajay Singh is a tenured Professor of Oncologic Sciences. He also leads a multi-disciplinary research program in Cancer Health Disparities. His laboratory primarily focuses on the molecular mechanisms involved in cancer progression and chemoresistance, and development of novel mechanism-based approaches for cancer therapy and prevention. He received his Ph.D. in Life Science from Devi Ahilya University, India, and postdoctoral training in Cancer Biology at UNMC/Eppley Cancer Institute, Omaha, Neb. He has received numerous honors and awards, both in India and the U.S., for his scientific accomplishments. Research programs in his laboratory have been supported through funding from NIH/NCI, DOD, and Nebraska and Alabama’s health departments. He also serves as a Co-PI on a NSF-MRI project that established TEM core facility at the University to benefit ongoing research programs and training of next-generation biomedical engineers and research professionals. Dr. Singh actively serves on DOD and NIH study sections and has been on the review panel boards of other national and international funding agencies and private foundations that provide support for cancer research.

Focus

This lab focuses on the functioning of the tumor cells at the molecular level. Specifically, lab members are interested in understanding how the tumor cells communicate with its surroundings to attain a variety of malignant phenotypes and if targeting of these tumor-stromal cell interactions could be exploited for cancer prevention and therapy. Another focus is to understand the molecular dissimilarities in tumors from patients of different racial backgrounds and investigate their roles in cancer health disparities.

Learn more about the Head, Tumor Microenvironment Lab.

Research Interests

  • Molecular mechanisms involved in cancer progression and chemoresistance
  • Cancer progression and metastasis
  • Therapeutic resistance in cancer
  • Tumor-stromal interactions
  • Molecular bases of cancer health disparities
  • MicroRNAs in cancer
  • Molecular diagnosis, prognosis and sub-classification of cancer
  • Natural products as cancer prevention and therapy agents

Education

  • Graduate: Biotechnology, Aligarh M. University | India
  • Postgraduate: Life Science, Devi Ahilya University | India

Research Location

USA Health has a comprehensive biomedical research program that spans a wide range of clinical, basic and translational research.​ At the Mitchell Cancer Institute, our physicians and scientific investigators are searching for breakthrough discoveries to improve the lives of cancer patients.

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