Scientists at the USA Health Mitchell Cancer Institute are examining how pancreatic cancer cells adapt to live under low-oxygen environments, a state known as hypoxia.
About Ajay Singh
Dr. Ajay Singh is a tenured Professor of Oncologic Sciences. He also leads a multi-disciplinary research program in Cancer Health Disparities. His laboratory primarily focuses on the molecular mechanisms involved in cancer progression and chemoresistance, and development of novel mechanism-based approaches for cancer therapy and prevention. He received his Ph.D. in Life Science from Devi Ahilya University, India, and postdoctoral training in Cancer Biology at UNMC/Eppley Cancer Institute, Omaha, Neb. He has received numerous honors and awards, both in India and the U.S., for his scientific accomplishments. Research programs in his laboratory have been supported through funding from NIH/NCI, DOD, and Nebraska and Alabama’s health departments. He also serves as a Co-PI on a NSF-MRI project that established TEM core facility at the University to benefit ongoing research programs and training of next-generation biomedical engineers and research professionals. Dr. Singh actively serves on DOD and NIH study sections and has been on the review panel boards of other national and international funding agencies and private foundations that provide support for cancer research.
This lab focuses on the functioning of the tumor cells at the molecular level. Specifically, lab members are interested in understanding how the tumor cells communicate with its surroundings to attain a variety of malignant phenotypes and if targeting of these tumor-stromal cell interactions could be exploited for cancer prevention and therapy. Another focus is to understand the molecular dissimilarities in tumors from patients of different racial backgrounds and investigate their roles in cancer health disparities.