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19-396 - Left Heart Chamber Disorder(Atrial) and Blood Clotting Medications used in Prevention After a Stroke of Unknown Origin

Status: open

AtRial Cardiopathy and Antithrombotic Drugs In prevention After cryptogenic stroke

Stroke Prevention

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ARCADIA is a multicenter, biomarker-driven, randomized, double-blind, active-control, phase 3 clinical trial of apixaban versus aspirin in patients who have evidence of atrial cardiopathy and a recent stroke of unknown cause. Eleven hundred subjects will be recruited over 2.5 years at 120 sites in the NINDS StrokeNet consortium. Subjects will be followed for a minimum of 1.5 years and a maximum of 4 years for the primary efficacy outcome of recurrent stroke and the primary safety outcomes of symptomatic intracranial hemorrhage and major hemorrhage other than intracranial hemorrhage.

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