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Yaguang Xi, M.D., Ph.D., MBA

Yaguang Xi, M.D., Ph.D., MBA
Associate Professor of Oncologic Sciences

USA Mitchell Cancer Institute
1660 Springhill Avenue
Mobile, Alabama 36604
(251) 445-9857
xi@health.southalabama.edu

Professional Profile

Research Interests:
- Discovery and validation of novel biomarkers associated with tumor progression, metastasis, therapeutic response, and chemoprevention
- Identification and characterization of important roles of non-coding RNA (microRNAs) in human cancer
- Developing novel normalization methods for microarray analysis

Education:
- M.D., Inner Mongolia Medical University, China
- Ph.D., Peking University, China
- MBA, University of South Alabama

Professional Appointments:
- Associate Professor of Oncologic Sciences, USA Mitchell Cancer Institute (2014-date)
- Assistant Professor of Oncologic Sciences, USA Mitchell Cancer Institute (2008-2014)

Honors and Academic Achievements:
- American Society of Clinical Oncology, Merit Award (2008)
- American Association for Cancer Research Aflac Scholar-In-Training Award (2007 & 2008)
- World Health Organization- International Agency for Research on Cancer, Special Training Award, France (2004)
- Outstanding Academic Researcher Award, Peking University, China (2003)
- Innovation Award, Peking University, China (2002)

Professional Memberships:
- American Association for Cancer Research
- American Society of Clinical Oncology
- International Honor Society Beta Gamma Sigma

Other Professional Honors / Services:
- Editorial Board Member: Acta Pharmacologica Sinica, American Medical Journal, Dataset Papers in Biology, Journal of Comparative Clinical Pathology Research, Journal of Integrative Oncology, microRNA, The Scientific World Journal, Thoracic Cancer
- Article Reviewer: Annals of Oncology, BBA - General Subjects, BMC Boinformatics, BMC Cancer, BMC Clinical Pathology, BMC Genomics, British Journal of Cancer, British Journal of Medicine and Medical Research, British Journal of Pharmacology, Chemotherapy, Clinical and Experimental Hypertension, Clinical Oncology and Cancer Research, Critical Reviews in Oncology/Hematology, Genomics, Proteomics & Bioinformatics, International Journal of Biomedical Science, International Journal of Cancer, International Journal of Immunogenetics, Journal of Chemotherapy, Journal of Nucleic Acids, Journal of Translational Medicine, Microarray, Molecular Cancer, Molecular Oncology, Medicinal Research Reviews, Nature Communications, Ochsner Journal, PloS ONE.
- Grant Reviewer: Genesis Oncology Trust, New Zealand (2011); Peer Reviewed Cancer Research Program, DOD (2012); Cell, Computational, and Molecular Biology Study Section, NIH/CSR (2012&2013); NCI R03 Cancer Prevention Study Section, NIH/NCI (2013); Research Grant Council (RGC), Hong Kong (2012-date); Cancer Drug Development and Therapeutics Study Section, NIH/CSR (2012-date)

Selected Publications (56 in total):
1. Xiangling Feng, Zhangming Wang, Rebecca Fillmore, Yaguang Xi. 2014. MiR-200, a new star microRNA in human cancer. Cancer Letters. 344(2):166-73.

2. Zhengming Wang, Wenjun Du, Gary A. Piazza, Yaguang Xi. 2013. MicroRNA is involved in self-renewal and differentiation of cancer stem cells. Acta Pharmacologica Sinica. 34(11):1374-80.

3. Bin Wang, Yaguang Xi. 2013. Challenges for MicroRNA Microarray Data Analysis. Microarrays 2(2): 34-50.

4. Bin Yi, Gary A. Piazza, Xiulan Su, Yaguang Xi. 2013. MicroRNA and Cancer Chemoprevention. Cancer Prev Res (Phila). 6(5):401-9.

5. Yaguang Xi. 2013. MicroRNA: A New Player for Cancer Chemoprevention. J Integr Oncol 1:2

6. Shen Guomin, Li, Xiaobo, Jia Yongfeng, Gary A. Piazza, Yaguang Xi. 2013. Hypoxia regulated microRNA in human cancer. Acta Pharmacologica Sinica. 34(3):336-41

7. Bin Wang, Shu-Guang Zhang, Xiao-Feng Wang, Ming Tan, Yaguang Xi. 2012. Testing for Differentially-Expressed MicroRNAs with Errors-in-Variables Nonparametric Regression. PLoS One. 7(5):e37537.

8. Xiaobo Li, Lin Gao, Qinghua Cui, Bernard D. Gary, Donna Lynn Dyess, William Taylor, Lalita A. Shevde, Rajeev S. Samant, Windy Dean-Colomb, Gary A. Piazza, Yaguang Xi. 2012. Sulindac inhibits tumor cell invasion by suppressing NF-κB mediated transcription of microRNAs. Oncogene. 31(48):4979-86

9. Lin Gao, YanhuiGao, Xiaobo Li, Paul Howell, Rajeev Kumar, Xiulan Su, Alexander V. Vlassov, Gary A. Piazza, Adam I. Riker, Dianjun Sun, Yaguang Xi. 2012. Aquaporins mediate the chemoresistance of human melanoma cells to arsenite. Molecular Oncology. 6(1):81-87

10. Xiaobo Li, Junwu Zhang, Lin Gao, Steve McClellan, Michael A. Finan, Thomas W. Butler, Laurie B. Owen, Gary A. Piazza, Yaguang Xi. 2012. MiR-181 mediates cell differentiation by interrupting the Lin28 and let-7 feedback circuit. Cell Death & Differentiation. 19(3):378-386.

11. Xiaobo Li, Caitlin Wainscott, Yaguang Xi. 2011. MicroRNA provides insight for understanding esophageal cancer. Thoracic Cancer. 2(4): 134-142.

12. Bin Wang, Paul Howell, Skjalg Bruheim, Jingfang Ju, Laurie Owen, Oystein Fodstad, Yaguang Xi. 2011. Systematic evaluation of three microRNA profiling platforms: microarray, beads array, and quantitative real-time PCR array. PLoSONE. 6(2):e17167.

13. Rajeev Kumar,Yaguang Xi. 2011. MicroRNAs, epigenetic machinery, and lung cancer. Thoracic Cancer. 2(2): 35–44

14. Paul Howell, Xiaobo Li, Adam I. Riker, Yaguang Xi. 2010. MicroRNA in Melanoma. Ochsner Journal. 10(2): 83-92.

15. Bin Wang, Xiao-Feng Wang, Howell Paul, XueminQian, Kun Huang, Adam Riker, JingfangJu, Yaguang Xi. 2010. A personalized microRNA microarray normalization method using a logistic regression model. Bioinformatics. 26(2):228-234.

Book: Skin Cancer Overview, Yaguang Xi (Ed.), 2011, ISBN: 978-953-307-746-8, InTech.

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