Applying interdisciplinary research techniques in molecular biology, toxicology, and biophysics to examine the gene-environment interactions of endocrine-disrupting chemical exposure. Understanding the underlying mechanisms modulating DNA damage response and repair will provide insight into future therapeutic intervention for EDC-exposed individuals.
Natalie R. Gassman, Ph.D.: Assistant Professor of Oncologic Sciences
Nathaniel Holton, Ph.D.: Postdoctoral fellow-DNA damage signaling and repair
Varsha Pednekar, Ph.D.: Postdoctoral fellow-Environmental toxicology and DNA repair
Micro-irradiation induces site-specific DNA damage that can be used to monitor the recruitment of DNA repair proteins. Adapted from Gassman et al. DNA Repair 2015.
Cellular and Biomolecular Imaging
R00ES023813 Bisphenol A modulation of DNA repair triggered by environmental stress
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