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Dec. 7, 2015 - MCI researchers present at USA College of Medicine Research Forum

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See photos from the University of South Alabama College of Medicine's 9th Annual Research Forum.

Several researchers from the USA Mitchell Cancer Institute presented findings related to topics ranging from DNA repair to new therapies for breast cancer at the 9th Annual College of Medicine Research Forum on Friday, Dec. 4, on the University of South Alabama campus.

Drs. Anna Wilk, Shruti Desai, Bin Yi and Natalie Gassman, all of MCI, were among nine presenters from the College of Medicine and MCI, which co-sponsored the event. In addition, 57 posters were displayed and presented at the USA Medical Sciences Building.

Dr. Samuel Strada, dean of the USA College of Medicine said that the forum was created about 10 years ago to increase awareness of research, promote collaboration and give researchers experience in presentations.

“What you’re going to see from the presentations today is an incredible number of cross collaborations,” said Dr. Laurie Owen, associate director for Basic and Translational Research at MCI. “Events like this really help drive these interactions. At MCI, we’re very open to cross-collaboration.”

One graduate student and one post-doctoral fellow, chosen by the judges for their presentations, will receive awards of $1,000 each for travel to national or international meetings. The travel awards are supported by the Basic Medical Sciences Student Organization, the College of Medicine Dean’s Office, the USA Graduate School and MCI.

To learn more about participating in the annual fForum, contact Dr. Donna Cioffi at

Topics for MCI presenters included:

Wilk, A.: “Hyper activation of poly (ADP-ribose) polymerase 1 (PARP1) triggers global metabolic alternations in a cellular model of gioblastoma”

Desai, S.: “Rose of heat shock factor 1 in chemotherapy induced endoplasmic reticulum stress response”

Yi, B.: “Inhibition of breast cancer cell metastiasis with a non-cyclooxygenase inhibitory derivative of sulindac by suppressing TGFβ/miR-21 signaling”

Gassman, N.: “Bishphenol A alters cellular microenvironment to promote survival after oxidative stress”

Topics for MCI posters included:

Andrews, J.: “PAR regulation of mitochondrial biology”

Averett, C.: “Honokiol attenuates stemness, growth and metastasis of pancreatic tumor cells: a novel natural agent for therapy and prevention”

Chang, H.: “CRISPR/cas9, an innovative genomic tool to know down microRNA invitro and invivo.”

Clark, D.C.: “FANCJ is important for the stability of FANCD2/FANCI proteins and protects them from proteasome and caspase-3 dependent degradation”

Daniels, C.L.: “Glycoproteomic analysis and comparison of colon cancer and colon adenoma gastrointestinal lavage fluid samples”

Deshmukh, S.K.: “Clinical relevance of resistin: an inflammatory cytokine, in breast cancer radial disparity”

Fang, Q.: “Altered mechanisms of stability for somatic mutants of DNA polymerase β”

Lee, K.: “β-catenin nuclear translocation in colorectal cancer cells is suppressed by PDE10A inhibition, cGMP elevation, and activation of PKG”

Li, J.: “Quantitative, real-time analysis of base excision repair activity using lesion-specific molecular beacons”

Liang, Z.: “Sulindac inhibition of tumor cell transformation”

Liu, Z.: “B7-H3 regulates cancer stem cell enrichment and chemoresistance through MVP/MAPK signaling pathway”

Otto, J.J.: “Peptide binding profile as a potential diagnostic in pancreatic cancer”

Patton, M.C.: “Hypoxic pancreatic cancer cells offer survival benefit through extracellular mechanisms”

Pednekar, V.: “Effects of low-dose BPA on cell proliferation and cancer metastasis”

Phillips, J.B.: “Regulation of RNA splicing of the ErbB family receptors by the splicing co-factor SON”

Rocker, J.M.: “Colonoscopy effluent: a less invasive method of sampling pancreatic secretions”

Smith, K.: “MST4 promotes cell growth and survival and reverses epithelial-to-mesenchymal transition in breast cancer”

Spencer, S.M.: “Rad6 inhibition attenuates activation of multiple DNA repair networks and sensitizes ovarian cancer cells to platinum drugs”

Stone, J.K.: “NFATC1 regulates express of the long non-coding RNA MALAT1”

Sullivan, M.: “The impact of university-based employee colorectal cancer screening initiatives in Alabama”

Sykora, P.: “Next generation high capacity DNA damage detection assay for compound screening”

Tyagi, N.: “P21-activated kinase 4 (PAK4) in pancreatic cancer: an emerging therapeutic target”

Williams, B.F.: “Elucidating the role of the functional microbiome in pancreatic cancer onset and progression”

Zhao, H.: “Sylindac inhibition of colon tumor cell growth through miRNA182/FOXO3a Cyclin  signaling”

Lim, S.: “The immunoregulatory protein B7-H3 regulates reprogramming of cancer cell glucose metabolism through reactive oxygen species mediated stabilization of HIF-1α”








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