Studies on the genetics metabolism and virulence of the agent causing epidemic typhus.
B Lymphocyte Biology:
Microenvironmental signals regulating B lymphocyte differentiation and cell fate.
Understanding molecular adaptation and transmission of avian influenza virus to humans, developing improved high-throughput assay systems to support clinical/ preclinical studies in vaccine development, developing efficient gene delivery vector, and understanding molecular pathogenesis determinant of emerging viruses in animal models.
Director, Laboratory of Infectious Diseases
Molecular pathogenesis of emerging and re-emerging viral infections, and the development of animal models and assays to support early stage discovery and evaluation of new medical interventions against an array of infectious disease pathogens.
David O. Wood, Ph.D.
Genetic and proteomic analysis of rickettsial obligate intracellular parasitism: Investigations of intracellular growth and virulence of the bacterial agents that cause Epidemic Typhus (Rickettsia prowazekii) and Rocky Mountain spotted fever (Rickettsia rickettsii).
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