Topics and Speakers for 2016

Nov. 8, 2016, Troy Stevens, Ph.D.
Formation of Plexiform Lesions in Experimental Severe Pulmonary Arterial Hypertension, Part 2
K. Abe, et al. Circulation. 2010;121:2747-2754. doi: 10.1161/CIRCULATIONAHA.109.927681

Nov. 1, 2016, Sabrina Ramelli
Intranasal administration of CpG oligodeoxynucleotides reduces lower airway inflammation in amurinemodel of combined allergic rhinitis and asthma syndrome
H-t Li, et al. International Immunopharmacology. 28 (2015) 390–398. Available at:

Oct. 25, 2016, April Scruggs
"Microparticle Uptake by Pulmonary Microvascular Endothelial Cells"

Oct. 18, 2016, Troy Stevens, Ph.D.
Formation of Plexiform Lesions in Experimental Severe Pulmonary Arterial Hypertension, Part 1
K. Abe, et al. Circulation. 2010;121:2747-2754. doi: 10.1161/CIRCULATIONAHA.109.927681

Oct. 11, 2016, Naga S. Annamdevula
“5 dimensional Hyperspectral and fret imaging to measure cAMP and PKA activity in PMVECs"

Sep. 27, 2016, Wito Richter, Ph.D, Abigail Boyd, and Ganga Baskar
“PDE4 as a therapeutic target"

Sep. 13, 2016, William "Jet" Broughton, M.D.
"Prion Disease"

Sep. 6, 2016, Michael Francis, Ph.D.
Advancing second messenger signal analysis
C.M. Francis, et al. Circ Res. 2016 Apr 1;118(7):1078-90. doi: 10.1161/CIRCRESAHA.115.308141.

Aug. 30, 2016, Richard Teplick, M.D.
“Choosing a career trajectory in medicine: lessons learned from my 46-year experience”

May 10, 2016, Mark N. Gillespie, Ph.D.
“Epigenetic Regulation of Transcription in Hypoxic Cells by Controlled Oxidative DNA 'Damage' and Repair"

May 3, 2016, Christiaan Ochoa, M.D.
Real-time resolution of point mutations that cause phenovariance in mice
T. Wang, et al. PNAS. 2015 112 (5) E440-E449; published ahead of print January 20, 2015, doi:10.1073/pnas.1423216112 

Apr. 26, 2016, Caleb Hamilton
Activated Rac1 GTPase Translocates Protein Phosphatase 5 to the Cell Membrane and Stimulates Phosphatase Activity in Vitro
A. Chatterjee, et al. The Journal of Biological Chemistry Vol. 285, NO. 6, pp. 3872–3882, February 5, 2010. Available at

Apr. 19, 2016, Kathleen McClinton
Glycosylation Is Required for Outer Membrane Localization of the Lectin LecB in Pseudomonas aeruginosa
K-M Bartels, et al. Journal of Bacteriology, Mar. 2011, p. 1107–1113 Vol. 193, No. 5. doi:10.1128/JB.01507-10

Apr. 12, 2016, Ed Crockett
Retrograde heart perfusion: The Langendorff technique of isolated heart perfusion
R.M. Bell, et al. Journal of Molecular and Cellular Cardiology 50 (2011) 940–950. doi:10.1016/j.yjmcc.2011.02.018

Mar. 29, 2016, Sabrina Ramelli
High IFN-γ and low SLPI mark severe asthma in mice and humans
M. Raundhal, et al. J Clin Invest. 2015;125(8):3037-3050. doi:10.1172/JCI80911.

Mar. 22, 2016, Kaori Oshima
Three-Dimensional Reconstruction of Pulmonary Arteries in Plexiform Pulmonary Hypertension Using Cell-Specific Markers
C.D. Cool, et al. American Journal of Pathology, Vol. 155, No. 2, August 1999.

Mar. 8, 2016, Lauren Cichon
Matrix Stiffness Regulates Endothelial Cell Proliferation through Septin 9
Y-T Yeh, et al. 2012. PLoS ONE 7(10):e46889. doi:10.1371/journal.pone.0046889

Mar. 1, 2016, Adam Morrow, Ph.D.
Secretion of the Toxin ExoU Is a Marker for Highly Virulent Pseudomonas aeruginosa Isolates Obtained from Patients with Hospital-Acquired Pneumonia
G.S. Schulert, et al. The Journal of Infectious Diseases. 2003;188:1695–706. available at

Feb. 23, 2016, Ningyong Xu
Cellular mechanisms of direct-current electric field effects: galvanotaxis and metastatic disease
M.E. Mycielska, et al. Journal of Cell Science 117, 1631-1639. Published by The Company of Biologists 2004. doi:10.1242/jcs.01125

Feb, 16, 2016, Joshua Deal
Principal component analysis with linear algebra
J. Jauregui. August 31, 2012.

Feb. 2, 2016, Phoibe Renema
"The role of cAMP in caspase-1 activation in PMVECs in response to Pseudomonas aeruginosa infection"

Jan. 27, 2016, Karen Fagan, M.D.
How to conduct a clinical trial
C. Nickson. Life in the Fastlane. Reviewed and revised 26 August 2015. Available at

Fundamentals of Clinical Trials
L.M. Friedman, et al. Fundamentals of Clinical Trials, 4th Ed.
Springer-Verlag New York (2010). XVIII, 445. doi 10.1007/978-1-4419-1586-3.

Jan. 26, 2016, Sarah McMurtry
“Celling Out:  Isolating Endothelial Cells for Fun and Profit”

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